I kēia lā, ua loaʻa iā mākou kahi nīnau hoihoi mai Velentium Medical, kahi hui e nīnau ana e pili ana i kā mākou lako o nā uea magnet biocompatible a me nā uea Litz, ʻo ia hoʻi nā mea i hana ʻia me ke kālā a i ʻole ke gula, a i ʻole nā mea hoʻonā insulation biocompatible ʻē aʻe. Pili kēia koi i ka ʻenehana hoʻouka uila uea ʻole no nā mea lapaʻau implantable.
Ua hālāwai ʻo Tianjin Ruiyuan Electrical Equipment Co., Ltd. me ia mau nīnau ma mua a ua hāʻawi i nā mea kūʻai aku me nā hopena kiʻekiʻe. Ua hana pū ka Ruiyuan Laboratory i kēia noiʻi ma ke gula, ke kālā, a me ke keleawe ma ke ʻano he mau mea bioimplantable:
I loko o nā mea lapaʻau implantable, hilinaʻi ka biocompatibility o nā mea i kā lākou launa pū ʻana me nā ʻiʻo kanaka, me nā mea e like me ke kūpaʻa ʻana i ka corrosion, ka pane ʻana o ka pale ʻana, a me ka cytotoxicity. Manaʻo nui ʻia ke gula (Au) a me ke kālā (Ag) he biocompatibility maikaʻi, ʻoiai ʻo ke keleawe (Cu) he biocompatibility haʻahaʻa, no kēia mau kumu:
1. Biocompatibility o ke gula (Au)
Ka inertness kemika: He metala hanohano ke gula ʻaʻole ia e oxidize a corrodes paha i loko o ke kaiapuni physiological a ʻaʻole hoʻokuʻu i ka nui o nā ions i loko o ke kino.
ʻO ka immunogenicity haʻahaʻa: ʻAʻole pinepine ke gula e hoʻoulu i ka mumū a i ʻole ka hōʻole ʻana o ka pale ʻana, e kūpono ai no ka hoʻokomo ʻana i ka wā lōʻihi.
2. Biocompatibility o ke kālā (Ag)
ʻO ka waiwai antibacterial: Loaʻa i nā ion kālā (Ag⁺) nā hopena antibacterial ākea, no laila ua hoʻohana nui ʻia lākou i nā implants pōkole (e like me nā catheters a me nā ʻaʻahu ʻeha).
Hoʻokuʻu ʻia e kaohi ʻia: ʻOiai e hoʻokuʻu ke kālā i kahi liʻiliʻi o nā ions, hiki i ka hoʻolālā kūpono (e like me ka nano-silver coating) ke hōʻemi i ka ʻawahia, hoʻopuka i nā hopena antibacterial me ka ʻole e hōʻino nui i nā cell kanaka.
Ka ʻawahia hiki: Hiki i ka nui o nā iona kālā ke hana i ka cytotoxicity, no laila pono e kaohi pono i ka nui a me ka helu hoʻokuʻu.
3. Biocompatibility o ke keleawe (Cu)
Ka hana kemika kiʻekiʻe: Hoʻopau maʻalahi ʻia ke keleawe i loko o ke kaiapuni wai o ke kino (e like me ka hoʻokumu ʻana iā Cu²⁺), a ʻo nā iona keleawe i hoʻokuʻu ʻia e hoʻoulu i nā hopena radical manuahi, e alakaʻi ana i ka hōʻino ʻana o nā cell, ka haki ʻana o ka DNA, a me ka denaturation protein.
Hopena pro-inflammatory: Hiki i nā ion keleawe ke hoʻoulu i ka ʻōnaehana pale, e hoʻoulu ai i ka mumū mau loa a i ʻole ka fibrosis kiko.
ʻO ka neurotoxicity: ʻO ka hōʻiliʻili nui ʻana o ke keleawe (e like me ka maʻi o Wilson) hiki ke hōʻino i ke akepaʻa a me ka ʻōnaehana nerve, no laila ʻaʻole kūpono ia no ka hoʻokomo lōʻihi.
Hoʻohana kūikawā: ʻO ka waiwai antibacterial o ke keleawe e ʻae iā ia e hoʻohana ʻia i nā mea lapaʻau pōkole (e like me nā uhi ʻili antibacterial), akā pono e kāohi pono ʻia ka nui o ka hoʻokuʻu ʻana.
Hōʻuluʻulu Manaʻo Koʻikoʻi
| Nā ʻano | Gula（AU） | Kāla (Ag) | Keleawe (Cu) |
| Ke kū'ē ʻana i ka palaho | Ikaika loa (ʻaʻohe hana) | Waena (Hoʻokuʻu lohi ʻia o Ag+) | Nāwaliwali (Hoʻokuʻu maʻalahi ʻia o Cu²+) |
| Pane pale ʻana | ʻAneʻane ʻaʻohe | Haʻahaʻa (Manawa hiki ke hoʻokele ʻia) | Kiʻekiʻe (Pro-inflammatory) |
| Ka ʻawahia ʻana o ka ʻōpū | ʻAʻohe | Waena-kiʻekiʻe (Ma muli o ka noʻonoʻo ʻana) | Kiʻekiʻe |
| Nā hoʻohana nui | Nā electrodes/prostheses i hoʻokomo ʻia no ka manawa lōʻihi | Nā mea hoʻokomo antibacterial no ka manawa pōkole | Kākaʻikahi (Pono ka mālama kūikawā) |
Hopena
ʻOi aku ka makemake ʻia o ke gula a me ke kālā no nā mea hoʻokomo lāʻau lapaʻau ma muli o ko lākou haʻahaʻa o ka palaho a me nā hopena olaola hiki ke kāohi ʻia, ʻoiai ʻo ka hana kemika a me ka ʻawahia o ke keleawe e kaupalena ana i kona hoʻohana ʻana i nā mea hoʻokomo lōʻihi. Eia nō naʻe, ma o ka hoʻololi ʻana i ka ʻili (e like me ka uhi ʻana o ka oxide a i ʻole ka hoʻohuihui ʻana), hiki ke hoʻohana ʻia ka waiwai antibacterial o ke keleawe i kahi palena, akā pono e loiloi pono ʻia ka palekana.
Ka manawa hoʻouna: Iulai-18-2025
